BDBM3557 CHEMBL418967::N-(3-bromophenyl)-6,7-dipropoxyquinazolin-4-amine::PD153035 Analog 57

SMILES CCCOc1cc2ncnc(Nc3cccc(Br)c3)c2cc1OCCC

InChI Key InChIKey=ZBOJKFDQWQBBHE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 3557   

TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3557(N-(3-bromophenyl)-6,7-dipropoxyquinazolin-4-amine ...)
Affinity DataIC50: 0.170nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3557(N-(3-bromophenyl)-6,7-dipropoxyquinazolin-4-amine ...)
Affinity DataIC50: 0.174nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed