BDBM355448 N-[(1R)-1-(4-cyclopropyl-3- fluorophenyl)-2,2-dimethylpropyl]- 6-oxo-2-phenyl-1,6- dihydropyrimidine-4-carboxamide::US9815796, Example 539

SMILES CC(C)(C)[C@@H](NC(=O)c1cc(=O)[nH]c(n1)-c1ccccc1)c1ccc(C2CC2)c(F)c1

InChI Key InChIKey=PREOLRSTGDUTKC-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 355448   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM355448(US9815796, Example 539 | N-[(1R)-1-(4-cyclopropyl-...)
Affinity DataKi:  1.20nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
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Date in BDB:
10/13/2019
Entry Details
US Patent