BDBM35491 Benzoic acid 5-amino-1-(4-methoxy-benzenesulfonyl)-1H-pyrazol-3-yl ester::MLS000033898::SMR000014915::[5-amino-1-(4-methoxyphenyl)sulfonylpyrazol-3-yl] benzoate::[5-azanyl-1-(4-methoxyphenyl)sulfonyl-pyrazol-3-yl] benzoate::benzoic acid [5-amino-1-(4-methoxyphenyl)sulfonyl-3-pyrazolyl] ester::benzoic acid [5-amino-1-(4-methoxyphenyl)sulfonyl-pyrazol-3-yl] ester::cid_655490

SMILES COc1ccc(cc1)S(=O)(=O)n1nc(OC(=O)c2ccccc2)cc1N

InChI Key InChIKey=FQICFDBMQBCJDT-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 35491   

TargetCathepsin B(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM35491(MLS000033898 | benzoic acid [5-amino-1-(4-methoxyp...)
Affinity DataIC50: 9.56E+3nMpH: 6.8 T: 2°CAssay Description:Screening Center: Penn Center for Molecular Discovery Center Affiliation: University of Pennsylvania Network: Molecular Library Screening Center Netw...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details
PCBioAssay
TargetCathepsin B(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM35491(MLS000033898 | benzoic acid [5-amino-1-(4-methoxyp...)
Affinity DataIC50: 9.56E+3nMAssay Description:Screening Center: Penn Center for Molecular Discovery Center Affiliation: University of Pennsylvania Network: Molecular Library Screening Center Netw...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2011
Entry Details
PCBioAssay
TargetCathepsin G(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM35491(MLS000033898 | benzoic acid [5-amino-1-(4-methoxyp...)
Affinity DataIC50: 2.08E+4nMAssay Description:Screening Center: Penn Center for Molecular Discovery Center Affiliation: University of Pennsylvania Network: Molecular Library Screening Center Netw...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2011
Entry Details
PCBioAssay
TargetGenome polyprotein(WNV)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35491(MLS000033898 | benzoic acid [5-amino-1-(4-methoxyp...)
Affinity DataIC50: 105nMAssay Description:The HTS assay to identify Inhibitors of West Nile Virus (WNV) NS2bNS3 Proteinase was proposed by Dr Alex Strongin of the Burnham Institute XO1-MH0776...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetProcathepsin L(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM35491(MLS000033898 | benzoic acid [5-amino-1-(4-methoxyp...)
Affinity DataIC50: 5.00E+4nMAssay Description:Screening Center: Penn Center for Molecular Discovery Center Affiliation: University of Pennsylvania Network: Molecular Library Screening Center Netw...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
TargetKallikrein-5(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM35491(MLS000033898 | benzoic acid [5-amino-1-(4-methoxyp...)
Affinity DataIC50: 2.54E+3nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2011
Entry Details
PCBioAssay
TargetGenome polyprotein(WNV)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35491(MLS000033898 | benzoic acid [5-amino-1-(4-methoxyp...)
Affinity DataIC50: 105nMAssay Description:Inhibition of WNV NS2B-NS3 protease by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetNonstructural protein 3(ZIKV)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM35491(MLS000033898 | benzoic acid [5-amino-1-(4-methoxyp...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of N-terminal His6-tagged Zika virus NS2B (45 to 96 residues) - NS3 (1 to 177 residues) protease domain expressed in Escherichia coli BL21...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetGenome polyprotein(WNV)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35491(MLS000033898 | benzoic acid [5-amino-1-(4-methoxyp...)
Affinity DataIC50: 105nMAssay Description:Inhibition of West Nile virus NS2B (1393 to 1440 residues)-NS3 (1476 to 1687 residues) protease expressed in Escherichia coli BL21 (DE3) codon plus c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed