BDBM354704 Preparation of 4-((2R,5R)-5-(aminomethyl)-2-(trifluoromethyl)oxazolidin-3-yl)-2-(trifluoromethyl)benzonitrile::US9809583, Example 12

SMILES [O-][N+](=O)c1ccc(OC[C@@H]2CN([C@H](O2)C(F)(F)F)c2ccc(C#N)c(c2)C(F)(F)F)c(Cl)c1

InChI Key InChIKey=DORLRNCPEDNDOH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 354704   

TargetAndrogen receptor(Green monkey)
Dong-A St

US Patent
LigandPNGBDBM354704(US9809583, Example 12 | Preparation of 4-((2R,5R)-...)
Affinity DataIC50: 145nMAssay Description:In order to examine binding ability of the agonists of the present invention to androgen receptors, the following in-vitro experiment was performed. ...More data for this Ligand-Target Pair
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Date in BDB:
10/7/2019
Entry Details
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