BDBM354699 Preparation of (S)-3-((4-nitro-3-(trifluoromethyl)phenyl)amino)propane-1,2-diol::US9809583, Example 7

SMILES COC(=O)c1ccc(OC[C@@H]2CN([C@H](O2)C(F)(F)F)c2ccc(C#N)c(c2)C(F)(F)F)cc1

InChI Key InChIKey=KEJXAVVCHQONTG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 354699   

TargetAndrogen receptor(Green monkey)
Dong-A St

US Patent
LigandPNGBDBM354699(US9809583, Example 7 | Preparation of (S)-3-((4-ni...)
Affinity DataIC50: 15.7nMAssay Description:In order to examine binding ability of the agonists of the present invention to androgen receptors, the following in-vitro experiment was performed. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details
Go to US Patent