BDBM354662 US9809582, Example 4

SMILES COc1ccc(cc1OC)[C@H](Cc1c(Cl)c[n+]([O-])cc1Cl)OC(=O)c1ccc(CNCC(C(=O)O[C@@H]2CCN(C)C2)c2ccccc2)s1

InChI Key InChIKey=SKXHDLPEXLKRND-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 354662   

TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM354662(US9809582, Example 4)
Affinity DataIC50: 55nMAssay Description:Human M3 receptor membranes (15 μg/well) from Perkin Elmer are incubated with 0.52 nM Scopolamine Methyl Chloride, [N-methyl-3H] with or without...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details
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TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM354662(US9809582, Example 4)
Affinity DataIC50: 5.5nMAssay Description:PDE4B2 activity is detected using the LANCE Ultra cAMP homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay from Perkin E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details
Go to US Patent