BDBM3546 4-N-(3-bromophenyl)-7-methoxyquinazoline-4,6-diamine::CHEMBL96780::PD153035 Analog 46

SMILES COc1cc2ncnc(Nc3cccc(Br)c3)c2cc1N

InChI Key InChIKey=VQTRWXQSANIXPR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 3546   

TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3546(CHEMBL96780 | 4-N-(3-bromophenyl)-7-methoxyquinazo...)
Affinity DataIC50: 3.80nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3546(CHEMBL96780 | 4-N-(3-bromophenyl)-7-methoxyquinazo...)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed