BDBM354544 2-(6-((2-ethyl-6-(1- (2-(3- hydroxyazetidin-1- yl)-2- oxoethyl)piperidin- 4-yl)imidazo[1,2- b]pyridazin-3- yl)(methyl)amino) pyridin-2-yl)-5- fluorobenzonitrile::US9796719, Compound 213

SMILES CCc1nc2ccc(nn2c1N(C)c1cccc(n1)-c1ccc(F)cc1C#N)C1CCN(CC(=O)N2CC(O)C2)CC1

InChI Key InChIKey=GUUXNYMSNRSSJY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 354544   

TargetAutotaxin(Human)
Galapagos

US Patent
LigandPNGBDBM354544(2-(6-((2-ethyl-6-(1- (2-(3- hydroxyazetidin-1- yl)...)
Affinity DataIC50: 55nMAssay Description:Compound IC50 values are determined in a fluorescent hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using the fluorogenic autotax...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2019
Entry Details
Go to US Patent

LigandPNGBDBM354544(2-(6-((2-ethyl-6-(1- (2-(3- hydroxyazetidin-1- yl)...)
Affinity DataIC50: 55nMAssay Description:Compound IC50 values are determined in a hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using LPC as substrate.5 μL of a dil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2019
Entry Details
Go to US Patent