BDBM35454 2-cyclopropyl-4-quinolinecarboxylic acid::2-cyclopropylcinchoninic acid::2-cyclopropylquinoline-4-carboxylic acid::CC-PMLSC-DMA-P121::cid_275785

SMILES OC(=O)c1cc(nc2ccccc12)C1CC1

InChI Key InChIKey=HYOFXKNWXLKLSH-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35454   

LigandPNGBDBM35454(2-cyclopropyl-4-quinolinecarboxylic acid | cid_275...)
Affinity DataIC50: 5.00E+4nMpH: 7.0 T: 2°CAssay Description:The MKP-1 dose response assay SAR support Assay - has been developed to test the activity of a series Analog compounds synthesized by the PMLSC Chemi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details
PCBioAssay
TargetGlycogen synthase kinase-3 beta(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM35454(2-cyclopropyl-4-quinolinecarboxylic acid | cid_275...)
Affinity DataEC50: >3.00E+5nMAssay Description:Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details
PCBioAssay