BDBM354516 2-((2-ethyl-6- ((3S,4S)-3- hydroxy-4- morpholino- pyrrolidin-1- yl)imidazo[1,2- blpyridazin-3- yl)(methyl)amino)- 4-(4- fluorophenyl) thiazole-5- carbonitrilc::US9796719, Compound 184

SMILES CCc1nc2ccc(nn2c1N(C)c1nc(c(s1)C#N)-c1ccc(F)cc1)N1C[C@H](O)[C@H](C1)N1CCOCC1

InChI Key InChIKey=MYAKCMZXALXKAL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 354516   

TargetAutotaxin(Human)
Galapagos

US Patent
LigandPNGBDBM354516(2-((2-ethyl-6- ((3S,4S)-3- hydroxy-4- morpholino- ...)
Affinity DataIC50: 55nMAssay Description:Compound IC50 values are determined in a fluorescent hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using the fluorogenic autotax...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2019
Entry Details
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