BDBM354513 N-(1-(1-(3-((5- cyano-4-(4- fluorophenyl) thiazol-2- yl)(methyl)amino)- 2-ethylimidazo[1,2- b]pyridazin-6- yl)pyrrolidin-3- yl)piperidin-4-yl)- N-methylacetamide::US9796719, Compound 181

SMILES CCc1nc2ccc(nn2c1N(C)c1nc(c(s1)C#N)-c1ccc(F)cc1)N1CCC(C1)N1CCC(CC1)N(C)C(C)=O

InChI Key InChIKey=HIWCTYYPXROVMS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 354513   

TargetAutotaxin(Human)
Galapagos

US Patent
LigandPNGBDBM354513(N-(1-(1-(3-((5- cyano-4-(4- fluorophenyl) thiazol-...)
Affinity DataIC50: 55nMAssay Description:Compound IC50 values are determined in a fluorescent hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using the fluorogenic autotax...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2019
Entry Details
Go to US Patent