BDBM354507 (S)-2-(1-(3-((5- cyano-4-(4- fluorophenyl) thiazol-2- yl)(methyl)amino)- 2-ethylimidazo[1,2- b]pyridazin-6- yl)pyrrolidin-3- ylamino)-N,N- dimethylacetamide::US9796719, Compound 175

SMILES CCc1nc2ccc(nn2c1N(C)c1nc(c(s1)C#N)-c1ccc(F)cc1)N1CC[C@@H](C1)NCC(=O)N(C)C

InChI Key InChIKey=UFTWQJDNKYWXGC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 354507   

TargetAutotaxin(Human)
Galapagos

US Patent
LigandPNGBDBM354507((S)-2-(1-(3-((5- cyano-4-(4- fluorophenyl) thiazol...)
Affinity DataIC50: 55nMAssay Description:Compound IC50 values are determined in a fluorescent hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using the fluorogenic autotax...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2019
Entry Details
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