BDBM354292 1-(4-((2-((3-Aminobenzo[d]isoxazol-5-yl)amino)pyrimidin-4-yl)oxy)naphthalen-1-yl)-3-(3-(tert-butyl)-1-(4-(dimethylphosphoryl)phenyl)-1H-pyrazol-5-yl)urea::US9796742, Example 20

SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4ccc5onc(N)c5c4)n3)c3ccccc23)n(n1)-c1ccc(cc1)P(C)(C)=O

InChI Key InChIKey=PBPZCBJXCHRCIQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 354292   

TargetGlycogen synthase kinase-3 alpha(Human)
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US Patent
LigandPNGBDBM354292(1-(4-((2-((3-Aminobenzo[d]isoxazol-5-yl)amino)pyri...)
Affinity DataIC50: 68nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3 enzyme isoform (Invitrogen), are evaluated by determining the level of acti...More data for this Ligand-Target Pair
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Date in BDB:
9/23/2019
Entry Details
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