BDBM354275 N-(4-((4-(3-(3-(tert-Butyl)-1-(4-(dimethylphosphoryl)phenyl)-1H-pyrazol-5-yl)ureido)-naphthalen-1-yl)oxy)pyridin-2-yl)-2-methoxyacetamide::US9796742, Example 3

SMILES COCC(=O)Nc1cc(Oc2ccc(NC(=O)Nc3cc(nn3-c3ccc(cc3)P(C)(C)=O)C(C)(C)C)c3ccccc23)ccn1

InChI Key InChIKey=NIRQXTRCFOIXLG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 354275   

TargetGlycogen synthase kinase-3 alpha(Human)
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US Patent
LigandPNGBDBM354275(N-(4-((4-(3-(3-(tert-Butyl)-1-(4-(dimethylphosphor...)
Affinity DataIC50: 16nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3 enzyme isoform (Invitrogen), are evaluated by determining the level of acti...More data for this Ligand-Target Pair
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Date in BDB:
9/23/2019
Entry Details
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