BDBM3540 4-N-(3-bromophenyl)-7-N-methylquinazoline-4,7-diamine::4-[(3-Bromophenyl)amino]-7-(methylamino)quinazoline::CHEMBL92812::PD153035 Analog::PD153035 Analog 40

SMILES CNc1ccc2c(Nc3cccc(Br)c3)ncnc2c1

InChI Key InChIKey=NJCGPPRBJLJTPA-UHFFFAOYSA-N

Data  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 3540   

TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3540(CHEMBL92812 | 4-N-(3-bromophenyl)-7-N-methylquinaz...)
Affinity DataIC50: 7nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3540(CHEMBL92812 | 4-N-(3-bromophenyl)-7-N-methylquinaz...)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetEphrin type-B receptor 2(Human)
Protana

Curated by ChEMBL
LigandPNGBDBM3540(CHEMBL92812 | 4-N-(3-bromophenyl)-7-N-methylquinaz...)
Affinity DataKd:  2.19E+4nMAssay Description:Equilibrium binding constant for EPH receptor B2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEphrin type-B receptor 2(Human)
Protana

Curated by ChEMBL
LigandPNGBDBM3540(CHEMBL92812 | 4-N-(3-bromophenyl)-7-N-methylquinaz...)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of EPH receptor B2 using ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed