BDBM353252 N-(3,5-difluorobenzyl)-4-fluoro-3-[2-(1,2,3,6-tetrahydropyridin-4-yl)-1H-pyrrolo[2,3-b]pyridin-4-yl]aniline::US9796708, Example 484

SMILES Fc1cc(F)cc(CNc2ccc(F)c(c2)-c2ccnc3[nH]c(cc23)C2=CCNCC2)c1

InChI Key InChIKey=FZFWVJXKYSMWFN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 353252   

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Abbvie

US Patent
LigandPNGBDBM353252(N-(3,5-difluorobenzyl)-4-fluoro-3-[2-(1,2,3,6-tetr...)
Affinity DataIC50: 17nMAssay Description:CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent