BDBM352312 (R)-4-(3-(but-2- ynamido)piperidin-1-yl)- 5-fluoro-2,3-dimethyl- 1H-indole-7-carboxamide::US9802915, Example 243

SMILES Cc1[nH]c2c(cc(F)c(N3CCC[C@H](C3)NC(=O)C#C)c2c1C)C(N)=O

InChI Key InChIKey=FNXUQYGBCDUPKM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 352312   

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM352312(US9802915, Example 243 | (R)-4-(3-(but-2- ynamido)...)
Affinity DataIC50: 0.200nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
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