BDBM352280 CHEM-US-00046::US9802944, Example 1.09

SMILES [H][C@@]12CN(C[C@]1([H])CCN(CC2)C(=O)c1cc(OCC2CCOCC2)nc(c1)C1CC1)C(=O)c1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=TWEXRGJILZLBSH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 352280   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352280(US9802944, Example 1.09 | CHEM-US-00046)
Affinity DataIC50: 5nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent