BDBM352277 CHEM-US-00043::US9802944, Example 1.06

SMILES c1cc(c(cc1S(=O)(=O)N)F)C(=O)N2C[C@H]3CN(C[C@@H]3C2)C(=O)c4cc(nc(c4)OCC5CCOCC5)C6CC6

InChI Key InChIKey=PSYZVOHTXPSAHY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 352277   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352277(US9802944, Example 1.06 | CHEM-US-00043)
Affinity DataIC50: 7nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent