BDBM352196 3-{4-[5-Amino-4-(6- morpholin-4-ylmethyl-1H- indole-2-carbonyl)-pyrazol- 1-yl]-3-chloro-phenoxy}- benzonitrile::US9802920, Compound I-20

SMILES NCc1cccc(Oc2ccc(c(Cl)c2)-n2ncc(C(=O)c3cc4ccc(CN5CCOCC5)cc4[nH]3)c2N)c1

InChI Key InChIKey=XLSVPGNFNKEVJA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 352196   

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352196(3-{4-[5-Amino-4-(6- morpholin-4-ylmethyl-1H- indol...)
Affinity DataIC50: 1nMAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (F rster/Flouresence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
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