BDBM352193 3-{4-[5-Amino-4-(1H- benzoimidazole-2-carbonyl)- pyrazol-1-yl]-3-methyl- phenoxy}-benzamide::US9802920, Compound I-17

SMILES Cc1cc(Oc2cccc(c2)C(N)=O)ccc1-n1ncc(C(=O)c2nc3ccccc3[nH]2)c1N

InChI Key InChIKey=CGCOKPXGCZNKFG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 352193   

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352193(3-{4-[5-Amino-4-(1H- benzoimidazole-2-carbonyl)- p...)
Affinity DataIC50: 230nMAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (F rster/Flouresence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
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