BDBM352192 3-{4-[5-Amino-4-(1H- indole-2-carbonyl)-pyrazol- 1-yl]-3-chloro-phenoxy}- benzonitrile::US9802920, Compound I-16

SMILES Nc1c(cnn1-c1ccc(Oc2cccc(c2)C#N)cc1Cl)C(=O)c1cc2ccccc2[nH]1

InChI Key InChIKey=QUFHITNIALFENN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 352192   

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352192(3-{4-[5-Amino-4-(1H- indole-2-carbonyl)-pyrazol- 1...)
Affinity DataIC50: 82nMAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (F rster/Flouresence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
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