BDBM352190 US9802920, Compound I-14::{5-Amino-1-[4-(2,3- difluoro-phenoxy)-2-methyl- phenyl]-1H-pyrazol-4-yl}- (1H-indol-2-yl)-methanone

SMILES Cc1cc(Oc2cccc(F)c2F)ccc1-n1ncc(C(=O)c2cc3ccccc3[nH]2)c1N

InChI Key InChIKey=HIEFXXGMWQSWPF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 352190   

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352190({5-Amino-1-[4-(2,3- difluoro-phenoxy)-2-methyl- ph...)
Affinity DataIC50: 3nMAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (F rster/Flouresence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
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