BDBM352188 US9802920, Compound I-12::[5-Amino-1-(4- cyclopentyloxy-phenyl)-1H- pyrazol-4-yl]-(1H-indol-2- yl)-methanone

SMILES Nc1c(cnn1-c1ccc(OC2CCCC2)cc1)C(=O)c1cc2ccccc2[nH]1

InChI Key InChIKey=PXVVRGJNVSOPOJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 352188   

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352188([5-Amino-1-(4- cyclopentyloxy-phenyl)-1H- pyrazol-...)
Affinity DataIC50: 1.00E+3nMAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (F rster/Flouresence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
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