BDBM352183 US9802920, Compound I-7::[5-Amino-1-(3-methoxy-4- phenoxy-phenyl)-1H- pyrazol-4-yl]-(1H-indol-2- yl)-methanone

SMILES COc1cc(ccc1Oc1ccccc1)-n1ncc(C(=O)c2cc3ccccc3[nH]2)c1N

InChI Key InChIKey=KKQCPDLJJWEUBB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 352183   

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352183([5-Amino-1-(3-methoxy-4- phenoxy-phenyl)-1H- pyraz...)
Affinity DataIC50: 552nMAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (F rster/Flouresence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
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