BDBM352179 US9802920, Compound I-3::{5-Amino-1-[4-(pyridin-2- yloxy)-phenyl]-1H-pyrazol- 4-yl}-(1H-indol-2-yl)- methanone

SMILES Nc1c(cnn1-c1ccc(Oc2ccccn2)cc1)C(=O)c1cc2ccccc2[nH]1

InChI Key InChIKey=RMKDVCIXZWYURL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 352179   

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352179({5-Amino-1-[4-(pyridin-2- yloxy)-phenyl]-1H-pyrazo...)
Affinity DataIC50: 502nMAssay Description:The assay is a capture of radioactive 33P phosphorylated product through filtration. The interactions of Btk, biotinylated SH2 peptide substrate (Src...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
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