BDBM352045 US9802907, Compound 24

SMILES COc1ccccc1-c1ccc(cc1C#N)-c1nc(C)c([se]1)C(O)=O

InChI Key InChIKey=QFIRBTHRBCNMLO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 352045   

TargetXanthine dehydrogenase/oxidase(Human)
Jiangsu Atom Bioscience and Pharmaceutical

US Patent
LigandPNGBDBM352045(US9802907, Compound 24)
Affinity DataIC50: 1.67nMAssay Description:The inhibition of the activity of xanthine oxidase (XO) is tested through a coupled enzymatic reaction of xanthine oxidase, horseradish peroxidase (H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

TargetXanthine dehydrogenase/oxidase(Bovine)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM352045(US9802907, Compound 24)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of Bovine milk XO using xanthine as substrate assessed as decrease in uric acid level measured after 30 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed