BDBM352035 US9802907, Compound 14::US9802907, Compound 23::US9802907, Compound 35

SMILES Cc1nc([se]c1C(O)=O)-c1ccc(-c2ccccc2)c(c1)C#N

InChI Key InChIKey=DJWSKQZSUPNTPC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 352035   

TargetXanthine dehydrogenase/oxidase(Human)
Jiangsu Atom Bioscience and Pharmaceutical

US Patent
LigandPNGBDBM352035(US9802907, Compound 14 | US9802907, Compound 35 | ...)
Affinity DataIC50: 1.70nMAssay Description:The inhibition of the activity of xanthine oxidase (XO) is tested through a coupled enzymatic reaction of xanthine oxidase, horseradish peroxidase (H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Jiangsu Atom Bioscience and Pharmaceutical

US Patent
LigandPNGBDBM352035(US9802907, Compound 14 | US9802907, Compound 35 | ...)
Affinity DataIC50: 2.37nMAssay Description:The inhibition of the activity of xanthine oxidase (XO) is tested through a coupled enzymatic reaction of xanthine oxidase, horseradish peroxidase (H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Jiangsu Atom Bioscience and Pharmaceutical

US Patent
LigandPNGBDBM352035(US9802907, Compound 14 | US9802907, Compound 35 | ...)
Affinity DataIC50: 2.63nMAssay Description:The inhibition of the activity of xanthine oxidase (XO) is tested through a coupled enzymatic reaction of xanthine oxidase, horseradish peroxidase (H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

TargetXanthine dehydrogenase/oxidase(Bovine)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM352035(US9802907, Compound 14 | US9802907, Compound 35 | ...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of Bovine milk XO using xanthine as substrate assessed as decrease in uric acid level measured after 30 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed