BDBM351960 Preparation of (S)-3-methyl-4-(4-morpholinyl-7-phenylpyrido[4,3-d]pyrimidin-2-yl)morpholine) ::US9796732, Compound 27

SMILES C[C@H]1COCCN1c1nc(N2CCOCC2)c2cnc(cc2n1)-c1ccccc1

InChI Key InChIKey=PEHOYXFRZNCLOM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 351960   

TargetSerine/threonine-protein kinase mTOR(Human)
Shandong Luoxin Pharmaceutical Group Stock

US Patent
LigandPNGBDBM351960(Preparation of (S)-3-methyl-4-(4-morpholinyl-7-phe...)
Affinity DataIC50: 134nMAssay Description:The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent