BDBM3518 4-N-phenylquinazoline-4,7-diamine::CHEMBL330224::PD153035 Analog 17

SMILES Nc1ccc2c(Nc3ccccc3)ncnc2c1

InChI Key InChIKey=WYKOALHWZONWJR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 3518   

TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3518(CHEMBL330224 | 4-N-phenylquinazoline-4,7-diamine |...)
Affinity DataIC50: 100nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3518(CHEMBL330224 | 4-N-phenylquinazoline-4,7-diamine |...)
Affinity DataIC50: 100nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed