BDBM35167 indazole-benzimidazole, 3

SMILES COc1cc(ccc1O)-c1ccc2c(n[nH]c2c1)-c1nc2c(cccc2[nH]1)N1CCN(C)CC1

InChI Key InChIKey=KKMLIJHOUUKCSW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35167   

TargetProtein kinase C zeta type(Human)
Pfizer

LigandPNGBDBM35167(indazole-benzimidazole, 3)
Affinity DataIC50: 2.26nMpH: 7.5 T: 2°CAssay Description:Protein kinase C (PKC), zeta activity was measured by following the phosphorylation of a biotinylated peptide substrate in the presence of ATP using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
LigandPNGBDBM35167(indazole-benzimidazole, 3)
Affinity DataIC50: 4.10nMT: 2°CAssay Description:Protein kinase C (PKC), zeta activity was measured by following the phosphorylation of a biotinylated peptide substrate in the presence of ATP using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed