BDBM351597 N-(4-bromo-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl)-2-(6-fluoro-2-oxo-3,4-dihydroquinolin-1(2H)-yl)acetamide::US9796706, Compound 41

SMILES Fc1ccc2N(CC(=O)Nc3scc(Br)c3-c3ncn[nH]3)C(=O)CCc2c1

InChI Key InChIKey=AHZNJVVIJQWSOW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 351597   

TargetMitogen-activated protein kinase 10(Human)
Imago Pharmaceuticals

US Patent
LigandPNGBDBM351597(US9796706, Compound 41 | N-(4-bromo-3-(1H-1,2,4-tr...)
Affinity DataIC50: 100nMAssay Description:(1) Assay buffer #1 with 0.0025% Tween and 1 mM DTT was prepared using JNK buffer stock solution.(2) Assay buffer #2 with 0.025% BSA was prepared usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 8(Human)
Imago Pharmaceuticals

US Patent
LigandPNGBDBM351597(US9796706, Compound 41 | N-(4-bromo-3-(1H-1,2,4-tr...)
Affinity DataIC50: 100nMAssay Description:(1) Assay buffer #1 with 0.0025% Tween and 1 mM DTT was prepared using JNK buffer stock solution.(2) Assay buffer #2 with 0.025% BSA was prepared usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 9(Human)
Imago Pharmaceuticals

US Patent
LigandPNGBDBM351597(US9796706, Compound 41 | N-(4-bromo-3-(1H-1,2,4-tr...)
Affinity DataIC50: 100nMAssay Description:(1) Assay buffer #1 with 0.0025% Tween and 1 mM DTT was prepared using JNK buffer stock solution.(2) Assay buffer #2 with 0.025% BSA was prepared usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
Go to US Patent