BDBM351582 N-(4-methyl-3-(3-methyl-1H-1,2,4-triazol-5-yl)thiophen-2-yl)-2-(quinolin-5-yl)acetamide::US9796706, Compound 26

SMILES Cc1n[nH]c(n1)-c1c(C)csc1NC(=O)Cc1cccc2ncccc12

InChI Key InChIKey=YPUXXNJBUOZMOQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 351582   

TargetMitogen-activated protein kinase 10(Human)
Imago Pharmaceuticals

US Patent
LigandPNGBDBM351582(US9796706, Compound 26 | N-(4-methyl-3-(3-methyl-1...)
Affinity DataIC50: 100nMAssay Description:(1) Assay buffer #1 with 0.0025% Tween and 1 mM DTT was prepared using JNK buffer stock solution.(2) Assay buffer #2 with 0.025% BSA was prepared usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 8(Human)
Imago Pharmaceuticals

US Patent
LigandPNGBDBM351582(US9796706, Compound 26 | N-(4-methyl-3-(3-methyl-1...)
Affinity DataIC50: 100nMAssay Description:(1) Assay buffer #1 with 0.0025% Tween and 1 mM DTT was prepared using JNK buffer stock solution.(2) Assay buffer #2 with 0.025% BSA was prepared usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 9(Human)
Imago Pharmaceuticals

US Patent
LigandPNGBDBM351582(US9796706, Compound 26 | N-(4-methyl-3-(3-methyl-1...)
Affinity DataIC50: 5.05E+3nMAssay Description:(1) Assay buffer #1 with 0.0025% Tween and 1 mM DTT was prepared using JNK buffer stock solution.(2) Assay buffer #2 with 0.025% BSA was prepared usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
Go to US Patent