BDBM351005 US9796700, Compound I-95

SMILES COc1cc(Nc2ncc(c(Nc3ccccc3NC(=O)C=C)n2)C(F)(F)F)cc(OC)n1

InChI Key InChIKey=BUMGUWUSPWVIHR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 351005   

TargetMitogen-activated protein kinase 3(Human)
Celgene Car

US Patent
LigandPNGBDBM351005(US9796700, Compound I-95)
Affinity DataIC50: 100nMAssay Description:The protocol below describes continuous-read kinase assays to measure potency of compounds against activated ERK1 enzyme. The mechanics of the assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
Go to US Patent