BDBM350966 US9796700, Compound I-55

SMILES CC(=O)N1CCC[C@@H](C1)Nc1ncc(c(Nc2ccccc2NC(=O)C(F)=C)n1)C(F)(F)F

InChI Key InChIKey=YLCAKYSTYLEGQO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 350966   

TargetMitogen-activated protein kinase 3(Human)
Celgene Car

US Patent
LigandPNGBDBM350966(US9796700, Compound I-55)
Affinity DataIC50: 100nMAssay Description:The protocol below describes continuous-read kinase assays to measure potency of compounds against activated ERK1 enzyme. The mechanics of the assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
Go to US Patent