BDBM350899 2-Benzylthio-3-phenyl-4-oxo-3,4-dihydroquinazoline ::US9796687, Compound 21

SMILES O=c1n(c(SCc2ccccc2)nc2ccccc12)-c1ccccc1

InChI Key InChIKey=STGAQMVRGXPRKM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 350899   

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM350899(US9796687, Compound 21 | 2-Benzylthio-3-phenyl-4-o...)
Affinity DataIC50: 600nMAssay Description:Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
Go to US Patent

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM350899(US9796687, Compound 21 | 2-Benzylthio-3-phenyl-4-o...)
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant PDE7A1 using [3H]AMP after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed