BDBM350546 US10208071, Compound 8::US10434112, Compound 90::US10799518, Compound 8::{[(2S)-2-{[(4- bromophenyl)carbamoyl]amino}-4- methylpentanoyl]amino}acetic acid

SMILES CC(C)C[C@H](NC(=O)Nc1ccc(Br)cc1)C(=O)NCC(O)=O

InChI Key InChIKey=LASJSIMHDHTROE-UHFFFAOYSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 350546   

TargetN-formyl peptide receptor 2(Human)
Allergan

US Patent
LigandPNGBDBM350546({[(2S)-2-{[(4- bromophenyl)carbamoyl]amino}-4- met...)
Affinity DataEC50:  780nMAssay Description:HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
Go to US Patent

TargetN-formyl peptide receptor 2(Human)
Allergan

US Patent
LigandPNGBDBM350546({[(2S)-2-{[(4- bromophenyl)carbamoyl]amino}-4- met...)
Affinity DataEC50:  780nMAssay Description:HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
Go to US Patent

TargetN-formyl peptide receptor 2(Human)
Allergan

US Patent
LigandPNGBDBM350546({[(2S)-2-{[(4- bromophenyl)carbamoyl]amino}-4- met...)
Affinity DataEC50:  11.6nMAssay Description:HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
Go to US Patent

TargetN-formyl peptide receptor 2(Human)
Allergan

US Patent
LigandPNGBDBM350546({[(2S)-2-{[(4- bromophenyl)carbamoyl]amino}-4- met...)
Affinity DataEC50:  780nMAssay Description:HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetN-formyl peptide receptor 2(Human)
Allergan

US Patent
LigandPNGBDBM350546({[(2S)-2-{[(4- bromophenyl)carbamoyl]amino}-4- met...)
Affinity DataEC50:  0.880nMAssay Description:Agonist activity at FPR2 (unknown origin) by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Allergan

US Patent
LigandPNGBDBM350546({[(2S)-2-{[(4- bromophenyl)carbamoyl]amino}-4- met...)
Affinity DataEC50:  0.780nMAssay Description:Agonist activity at human FPR2 expressed in HEK cells assessed as increase in calcium flux incubated for 40 mins by Fluo-4 staining based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed