BDBM350495 Methyl N-[(14S)-14-[1-(3-chloro-2-fluorophenyl)-5-methyl-1H-pyrazole-4-amido]-10-methyl-8-oxo-9,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-5-yl]carbamate, TFA salt::US10208068, Example 221

SMILES COC(=O)Nc1ccc2-c3ccnc(c3)[C@H](CCCC(C)NC(=O)c2c1)NC(=O)c1cnn(c1C)-c1cccc(Cl)c1F

InChI Key InChIKey=OQQKTDJHZHNHQB-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 350495   

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM350495(Methyl N-[(14S)-14-[1-(3-chloro-2-fluorophenyl)-5-...)
Affinity DataKi:  312nMAssay Description:The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
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