BDBM350494 US10208068, Example 207

SMILES COC(=O)Nc1ccc2C3C=NC(=N3)[C@H](CCC[C@@H](C)C(=O)Nc2c1)NC(=O)c1nnn(c1C)-c1c(F)ccc(Cl)c1F

InChI Key InChIKey=JMDXBUVBEHCTIV-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 350494   

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM350494(US10208068, Example 207)
Affinity DataKi:  153nMAssay Description:The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
Go to US Patent