BDBM350490 1-(3-Chloro-2-fluorophenyl)-5-methyl-N-[(10S,14S)-10-methyl-9-oxo-5-(1H-pyrazol-5-yl)-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-14-yl]-1H-1,2,3-triazole-4-carboxamide, TFA salt::US10208068, Example 165

SMILES C[C@H]1CCC[C@H](NC(=O)c2nnn(c2C)-c2cccc(Cl)c2F)c2cc(ccn2)-c2ccc(cc2NC1=O)-c1ccn[nH]1

InChI Key InChIKey=WBXRPMVLSQRSTG-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 350490   

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM350490(1-(3-Chloro-2-fluorophenyl)-5-methyl-N-[(10S,14S)-...)
Affinity DataKi:  5.08E+3nMAssay Description:The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
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