BDBM350486 US10208068, Example 151

SMILES CC1C(=NN=C1c1cccc(Cl)c1F)C(=O)N[C@H]1CCC[C@@H](C)C(=O)Nc2cc(Nc3ccncn3)ccc2-c2ccnc1c2

InChI Key InChIKey=XDEKSLNGQDHUDP-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 350486   

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM350486(US10208068, Example 151)
Affinity DataKi:  17.3nMAssay Description:The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
Go to US Patent