BDBM350466 Ethyl (9R,14S)-14-[1-(3-chloro-2-fluorophenyl)-1H-pyrazole-4-amido]-5-[(methoxycarbonyl)amino]-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaene-9-carboxylate, 2 TFA salt::US10208068, Example 26

SMILES CCOC(=O)C1CCCC[C@H](NC(=O)c2cnn(c2)-c2cccc(Cl)c2F)c2cc(ccn2)-c2ccc(NC(=O)OC)cc2N1

InChI Key InChIKey=IPNGLKJCOHBUPK-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 350466   

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM350466(Ethyl (9R,14S)-14-[1-(3-chloro-2-fluorophenyl)-1H-...)
Affinity DataKi:  178nMAssay Description:The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
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