BDBM350439 US10208066, Compound 61::US10611777, Compound 61

SMILES C[C@H](Nc1ncnc(N)c1C#N)c1cc2ncc(Cl)n2nc1-c1ccc2cccnc2c1

InChI Key InChIKey=VPKGTPCVDWWFAS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 350439   

LigandPNGBDBM350439(US10208066, Compound 61 | US10611777, Compound 61)
Affinity DataIC50: 7nMAssay Description:Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
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LigandPNGBDBM350439(US10208066, Compound 61 | US10611777, Compound 61)
Affinity DataIC50: 7nMAssay Description:PI3K kinases including p110α/p85α and p110γ were purchased from Invitrogen, p110δ/p85α and p110β/p85α were from Mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent