BDBM350405 US10208066, Compound 22::US10611777, Compound 22

SMILES C[C@H](Nc1ncnc(N)c1C#N)c1cc2ncc(C)n2nc1-c1ccccc1

InChI Key InChIKey=ONZNRDPLVLNHSG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 350405   

LigandPNGBDBM350405(US10208066, Compound 22 | US10611777, Compound 22)
Affinity DataIC50: 2nMAssay Description:Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM350405(US10208066, Compound 22 | US10611777, Compound 22)
Affinity DataIC50: 322nMAssay Description:Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM350405(US10208066, Compound 22 | US10611777, Compound 22)
Affinity DataIC50: 2nMAssay Description:PI3K kinases including p110α/p85α and p110γ were purchased from Invitrogen, p110δ/p85α and p110β/p85α were from Mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

LigandPNGBDBM350405(US10208066, Compound 22 | US10611777, Compound 22)
Affinity DataIC50: 322nMAssay Description:PI3K kinases including p110α/p85α and p110γ were purchased from Invitrogen, p110δ/p85α and p110β/p85α were from Mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent