BDBM350284 US10208064, Example 4

SMILES CC1=C(COC1=O)N1CC[C@]2(CCN(C[C@H](O)c3ccc-4c(Cn5nnnc-45)c3)C[C@H]2F)C1=O

InChI Key InChIKey=JRIWLLOBCGOEOS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 350284   

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Wuxi Apptec (Shanghai)

US Patent
LigandPNGBDBM350284(US10208064, Example 4)
Affinity DataIC50: 43nMAssay Description:A Thallium Flux Assay was performed on the compounds of the Examples. This assay has been described previously; see, e.g., PCT Published Application ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
Go to US Patent