BDBM350141 5-[8-amino-1-(4-{(1R)-1- hydroxy-1-[3- (trifluoromethyl)phenyl] ethyl}phenyl)imidazo[1,5- a]pyrazin-3- yl]bicyclo[3.2.2]nonane-1- carboxylic acid::US10208047, Example 9

SMILES C[C@@](O)(c1ccc(cc1)-c1nc(n2ccnc(N)c12)C12CCC(CC1)(CCC2)C(O)=O)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=AVIZEELGPHTKGW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 350141   

TargetTyrosine-protein kinase BTK(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM350141(US10208047, Example 9 | 5-[8-amino-1-(4-{(1R)-1- h...)
Affinity DataIC50: 7nMAssay Description:BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
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