BDBM350121 2-(4-oxo-1-(S,S,-dioxo- tetrahydrothiophen-3-yl)- 1H-pyrazolo[3,4-d] pyrimidin-5(4H)-yl)-N- (3-(trifluoromethyl) phenyl)acetamide::US10208043, # 23::US10941146, # 23

SMILES FC(F)(F)c1cccc(NC(=O)Cn2cnc3n(ncc3c2=O)C2CCS(=O)(=O)C2)c1

InChI Key InChIKey=JCINPOVXFDURCS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 350121   

TargetFascin(Human)
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350121(US10208043, # 23 | 2-(4-oxo-1-(S,S,-dioxo- tetrahy...)
Affinity DataIC50: 3.40E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
US Patent

TargetFascin(Human)
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350121(US10208043, # 23 | 2-(4-oxo-1-(S,S,-dioxo- tetrahy...)
Affinity DataIC50: 3.40E+3nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent