BDBM349996 (2R)-2-amino-N-(1-(3,5- bis(trifluoromethyl)phenoxy) propan-2-yl)-4-methylpentanamide::US10208023, No. 6

SMILES CC(C)C[C@@H](N)C(=O)NC(C)COc1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=UIWDLJLUALYZTQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 349996   

LigandPNGBDBM349996((2R)-2-amino-N-(1-(3,5- bis(trifluoromethyl)phenox...)
Affinity DataIC50: 1.66E+3nMAssay Description:NAV1.7 INWARD CURRENT BLOCK (nM) (Automated Patchclamp).More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
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LigandPNGBDBM349996((2R)-2-amino-N-(1-(3,5- bis(trifluoromethyl)phenox...)
Affinity DataIC50: 1.27E+4nMAssay Description:In some cases, the potency of compounds was measured using either the Patchliner automated patch clamp platform (Nanion) or manual patch clamp techni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
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LigandPNGBDBM349996((2R)-2-amino-N-(1-(3,5- bis(trifluoromethyl)phenox...)
Affinity DataIC50: 2.77E+3nMAssay Description:NAV1.7 SLOW INACTIVATION BLOCK (nM) (Automated Patchclamp).More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
Go to US Patent