BDBM348670 4-(Cyclopropylmethoxy)-N-[4-[(1S,3R,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-3-yl]phenyl]benzamide::US9790230, Example 32

SMILES O=C(Nc1ccc(cc1)[C@H]1O[C@@H]2CN[C@H]1C2)c1ccc(OCC2CC2)cc1

InChI Key InChIKey=QGXRGTMPETWYEO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 348670   

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM348670(4-(Cyclopropylmethoxy)-N-[4-[(1S,3R,4S)-2-oxa-5-az...)
Affinity DataIC50: 6.30nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
Go to US Patent

TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM348670(4-(Cyclopropylmethoxy)-N-[4-[(1S,3R,4S)-2-oxa-5-az...)
Affinity DataIC50: 164nMAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
Go to US Patent