BDBM348637 US10577374, Compound 360::US9790229, Compound 360

SMILES Fc1cc(Cl)cc(NC2CCCN([C@@H]3CCCN(C3)c3ncnc4[nH]ncc34)C2=O)c1

InChI Key InChIKey=COXQUJPRGLQAKZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 348637   

TargetTyrosine-protein kinase BTK(Human)
Sunesis Pharmaceuticals

US Patent
LigandPNGBDBM348637(US9790229, Compound 360 | US10577374, Compound 360)
Affinity DataIC50: 100nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Sunesis Pharmaceuticals

US Patent
LigandPNGBDBM348637(US9790229, Compound 360 | US10577374, Compound 360)
Affinity DataIC50: 100nMAssay Description:BTK-POLYGAT-LS ASSAY. The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Sunesis Pharmaceuticals

US Patent
LigandPNGBDBM348637(US9790229, Compound 360 | US10577374, Compound 360)
Affinity DataIC50: 15nMAssay Description:Inhibition of BTK (unknown origin) incubated 30 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed